Common aspects of Eucheuma denticulatum farming include using short, thin lines or loops to secure multiple small "seedlings" spaced at regular intervals to a longer, thicker line.  This longer line could be secured at either end to a stake, another line, a frame, or a raft.  Maintenance involves visiting each farming area 2 to 3 times per week to remove epiphyte algae growing on the Eucheuma denticulatum, tightening of loose lines, and checking for ice-ice and other signs of damage to the crop.  Harvesting occurs every 4 to 6 weeks, and depending on the method, can involve bringing in entire lines, or un-tying each piece of seaweed directly.  Regardless of cultivation method, the seaweed must be tried to around 35% moisture content, which could be achieved by drying on mats or fronds on the shore, or on a dock, or hanging from drying lines, or using more advanced methods such as with a solar tunnel drier.  A portion of each harvest (perhaps 10%) is retained to commence the next cycle.

The "off-bottom method" for cultivating Eucheuma denticulatum uses large stakes driven into the seabed in a rectangular shape.  A thicker line runs between the "ends" of the rectangle.  Between these ends, long (10 - 20 meter) thick lines are run, and the seedlings are secured to these long lines via "tie-ties".  An off-bottom farm may become exposed to open air for short periods of time at certain low tides, although it remains submerged most of the time.  An advantage of the off-bottom method is that it can be visited at slack and low tides without a boat, and it is often closer to the home of the farmer.  Disadvantages include proximity to rainwater runoff, which can reduce growth or trigger ice-ice disease, susceptability to higher temperatures, and also these shallow water farms can be more vulnerable to grazers such as rabbitfish.

The "long-line method" can be used in deeper water, and requires the use of floats, which can be small buoys, but are often simply empty plastic water jugs or bottles with the caps still secured.  Weighted blocks at either end anchor the line, floats are adjusted to provide the proper depth of theEucheuma denticulatum seaweed just below the surface.  These lines can be dozens of meters long.  An advantage of this approach is that much greater farming areas can be exploited by a farming community.  There are higher operational costs due to required use of boats, and more maintenance to periodically untangle the long lines.

The "raft method" of cultivation for Eucheuma denticulatum uses a material such as bamboo to construct on the order of 10-meter square rafts, which are in turn secured to the bottom by an anchor (often a concrete block).  Rafts are more expensive to construct, but they offer the convenience of being towed in to shore for harvest and replacement with new seedlings.  Then, the farmer can boat back with the replenished raft in tow to the float, and re-secure the raft.  In general, the rafts are less susceptible to becoming entangled with each other than the long lines.  A "basket method" has emerged in certain areas in the Philippines and Indonesia, which is similar to the raft method, but uses floating baskets.  There is an additional cost for the baskets, and more substantial floats are required, but work effort is reduced by eliminating the tedious work associated with tie-ties each harvest.